MSc Project: A Systematic Review of the Qiagen CLC Genomics Workbench for Differential Expression Analysis
Overview
This systematic review evaluates how the Qiagen CLC Genomics Workbench performs each stage of the RNA sequencing differential expression workflow. The project examines the underlying algorithms, compares CLC's implementation with established open source approaches, and assesses its strengths and limitations for researchers who prefer graphical interfaces over programming.
Research Question
Can the Qiagen CLC Genomics Workbench provide a reliable, end to end solution for differential expression analysis for scientists with little or no programming experience?
What I Did
Reviewed each stage of the differential expression workflow within CLC Genomics Workbench.
Examined the algorithms and statistical methods used throughout the workflow.
Compared CLC's methodology with published analyses performed using EdgeR.
Evaluated the advantages and limitations of a graphical user interface compared with command line bioinformatics tools.
Assessed the software's suitability for researchers without coding experience.
Key Contribution
This review provides an accessible resource for researchers considering Qiagen CLC Genomics Workbench as a complete graphical workflow for differential expression analysis, while discussing the tradeoffs between ease of use, flexibility, and analytical transparency.
Skills Demonstrated
Bioinformatics
RNA sequencing analysis
Differential gene expression
Literature review
Critical evaluation of scientific software
Scientific writing
Kopo Kopo Owners’ Manual v1 2025
Overview
A culture translation project that converts internal HR policy and behavioural principles into an accessible, narrative-driven learning format.
What I did
Converted a traditional HR policy and code of conduct document into an illustrated, narrative-based learning manual.
Translated formal HR language into accessible, conversational content without losing policy accuracy.
Designed a comic-style format to improve engagement and retention of behavioural and cultural principles.
Used AI-generated imagery to create visual storytelling elements that support key organisational scenarios.
Collaborated with team leadership to ensure that creative interpretation remained aligned with core organisational policies and intent.
Developed scenarios that demonstrate real workplace decision-making and reinforce cultural principles through storytelling.
Key Contribution
This project transforms static policy documentation into an engaging learning experience designed to be revisited, shared, and applied in day-to-day workplace decisions.
Skills Demonstrated
Instructional design and content simplification
Organisational communication
Visual storytelling and narrative design
AI-assisted content and image generation
Stakeholder collaboration
Policy interpretation and translation into user-friendly formats
